✦ Based on clinical trial data
How Much Weight Could You Lose on Ozempic or Mounjaro?
Enter your details and see a personalised estimate based on real clinical trial results from the STEP and SURMOUNT trials.
Common Questions
How much weight can I lose on Ozempic (semaglutide)?
Clinical trials (STEP program) show average weight loss of around 13.7% of body weight on Wegovy (semaglutide 2.4mg) over 68 weeks. At lower Ozempic doses used for diabetes, average loss is typically 6–9%. Individual results vary significantly based on diet, exercise and adherence.
Is Mounjaro better than Wegovy for weight loss?
According to the 2025 SURMOUNT-5 head-to-head trial published in the New England Journal of Medicine, tirzepatide (Mounjaro/Zepbound) produced average weight loss of 20.2% compared to 13.7% for semaglutide (Wegovy) — a 47% greater relative difference. However, both are highly effective medications.
How quickly do GLP-1 medications work?
Most people see initial results within 4–8 weeks. Significant weight loss typically builds over 3–6 months as doses are gradually increased. Peak results are usually seen at 12–18 months of consistent use.
Will I regain weight if I stop taking Ozempic or Mounjaro?
Clinical trials showed that most people regain a significant portion of lost weight when stopping these medications. However, a 2026 Cleveland Clinic real-world study of nearly 8,000 patients found better outcomes than trials suggested, as many patients restart medication or transition to lifestyle changes.
Do I need a prescription for GLP-1 weight loss medications?
Yes. Ozempic, Wegovy, Mounjaro and Zepbound all require a prescription from a licensed healthcare provider. They are approved for specific conditions — speak to your doctor about whether they're appropriate for you.
How much does Ozempic cost in Australia?
For type 2 diabetes patients, Ozempic is subsidised on the PBS at around $25–$31.60 per script (concession card holders pay ~$7.70). For weight loss use without diabetes, it's not PBS-subsidised and costs roughly $130–$260 per month privately. Wegovy and Mounjaro for weight loss are also available privately through telehealth providers at $200–$650/month depending on dose and service.